500 is designed with enhancements that put the power of treatment
in the hands of the physician. Physician control ensures customized,
tailored treatments for each patient. No two patients are exactly
the same; customization with the Sonablate® 500 allows the treating
physician to provide the patient with the best HIFU treatment possible.
- HIFU is "clean" energy; there is no
radiation exposure to the patient, so there is no risk for weakening
or damaging of cells and tissue surrounding the prostate.
- Sonablate® HIFU is non-surgical; therefore
there is minimal bloodloss and it is less invasive than other
treatments for Prostate cancer.
- HIFU is performed under spinal (epidural)
anesthesia, thus eliminating risk associated with general anesthesia.
- It is an out-patient procedure; no overnight
hospital stay is required.
- HIFU can be repeated, if necessary.
- After HIFU, if needed, patients may pursue other
treatment options (radiation, cryotherapy, surgery etc).
- HIFU with the Sonablate®
500 can be used as a salvage treatment for local prostate
- Studies show that HIFU preserves patient
quality of life by minimizing side effects such as impotence
No Surgery Required with the Sonablate® 500
The Sonablate® is the only HIFU device that
has the ability to treat up to a 45cc prostate without needing an
invasive procedure, such as a TURP (transurethral resection of the
prostate), prior to HIFU. The Ablatherm® device requires that
a TURP, an invasive surgical procedure, be performed prior to HIFU
for any prostate larger than 24cc. Due to the design of the probe
and the focal lengths of the transducer, the Sonablate® has
a 90-degree therapy zone that gives the physician immediate access
to the entire prostate gland without having to move or reposition
Sonablate® 500 has Superior Imaging
The benefit of real-time and reference images
that are unique to the Sonablate®
500 is that the physician can get immediate feedback for maximum
precision. The images are used as guidelines to customize and plan
the HIFU treatment. During HIFU these images are continuously monitored
and evaluated to show treatment progression and precision. The Sonablate®
500 also incorporates 3-Dimensional imaging for more accurate
500 has integrated hardware and software built into the device
which identifies the blood flow through the neurovascular bundles
(in these bundles run the nerves in charge of the sexual potency).
This means that as the physicians acquires real-time images of the
prostate, he/she is also able to locate the exact position of the
nerves bundles responsible for preserving potency. HIFU treatment
is planned by the physicians based on these images. Since the doctor
can clearly identify the location of the blood flow, he/she can
easily avoid causing damage to the nerves, thus fewer patients treated
with the Sonablate® 500 have problems with erectile dysfunction.
Click on the image to enlarge the screen shot of the neurovascular
bundle detection. The Ablatherm® is not capable of identifying
or monitoring blood flow through the neurovascular bundles during
HIFU at all. Therefore, the Ablatherm® has a much higher statistical
incidence of erectile dysfunction associated with outcomes.
Hands-On Physician Control
Using the Sonablate®
500, the physician controls the position and the placement of
the probe and can adjust it for optimal outcomes and comfort. Probe
movement with the Ablatherm® is limited because it is fixed
on the treatment table and not directly controlled by the physician
hands –on. Dynamic Power Adjustment
500 features dynamic power adjustment during HIFU to account
for tissue response to the delivery of energy. Additionally, the
physician has the ability to adjust power levels near vital areas
such as around nerve bundles and near the rectum. This feature adds
safety and further allows for customization of treatment. The Ablatherm®
has three pre-set power levels and it does not have the ability
to adjust based on tissue response. Therefore all patient treated
with the Ablatherm® are treated with the same power level, as
if they were all equal, which is not ideal.
The Most Precise Treatment Available
500 is designed to treat the prostate in multiple overlapping
zones. Ultrasound is focused on a small point within the focal zone
creating a small lesion where the tissue is heated and destroyed.
These lesions are placed side by side until all the tissue has been
destroyed. The Sonablate®
500 produces small lesions that are so precise, 12mm in length,
that the physician is able to be place them at the prostatic apex
while monitoring the rectal wall. The Ablatherm® produces a
larger lesion, 19-24mm at the focal point with a 1.7mm diameter
which must be placed 5-8mm behind the apex. This could leave some
prostatic tissue outside of the treatment zone, which is undesirable
and increase the chance for cancer recurrence.
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